NAD+
The molecule that powers every cell in your body — and runs out with age.
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every living cell that is essential for energy production, DNA repair, and the regulation of hundreds of metabolic processes. NAD+ levels decline by up to 50% between ages 40 and 60 — and this decline is now recognized as a central driver of the aging process.
The Science
How It Works
NAD+ is a critical substrate for sirtuins (longevity proteins) and PARP enzymes (DNA repair proteins). It is the primary electron carrier in cellular respiration — the process by which cells convert nutrients into ATP energy. Restoring NAD+ levels activates these longevity pathways, improves mitochondrial function, and enhances the cell's ability to repair DNA damage.
What to Expect
Key Benefits
Rapid Energy & Mental Clarity
Men consistently report dramatic improvements in energy, focus, and mental clarity — often within the first treatment. IV NAD+ produces the most immediate and pronounced effects.
Accelerated DNA Repair
NAD+ is essential for PARP enzyme function — the primary mechanism by which cells repair DNA damage. Restoring NAD+ dramatically improves cellular repair capacity.
Sirtuin Activation
Sirtuins are longevity proteins that regulate aging, inflammation, and metabolic health. They require NAD+ as a substrate — making NAD+ restoration essential for activating these pathways.
Improved Mitochondrial Function
NAD+ is the primary electron carrier in the mitochondrial electron transport chain. Restoring levels directly improves cellular energy production.
Addiction & Neurological Support
High-dose IV NAD+ has shown remarkable results in supporting recovery from addiction and neurological conditions — an area of growing clinical interest.
Find out if NAD+ is right for you.
A free 20-minute call with our physician team. No commitment required.
Who It's For
Men experiencing significant fatigue, brain fog, or the general sense of running on empty. Also ideal for men focused on longevity, cellular health, and maximizing the benefits of other optimization protocols.
Administration
Available as IV infusion (fastest and most dramatic results), subcutaneous injection, or oral precursors (NMN/NR). IV protocols typically run 4–10 days for an initial loading phase, followed by monthly maintenance infusions.
Safety Profile
NAD+ has an excellent safety profile. IV administration can cause mild flushing, nausea, or chest tightness if infused too rapidly — our protocols use slow infusion rates to minimize discomfort. Oral and injectable forms are very well tolerated.
Ready to Start a NAD+ Protocol?
Book a free consultation with our medical team. We'll review your labs and determine if NAD+ is right for your goals.